BIOLOGICAL ASSAY AND STANDARDISATION OF MELANOPHORE EXPANDING PITUITARY HORMONE

Regulation of melanophore stimulating hormone (MSH) release.

Melanin pigmentation of the vertebrate integument is regulated by melanophore-stimulating hormone (MSH) which originates from the pars intermedia of the pituitary gland (1). Early experiments established that MSH release, as for other pituitary secretions, was under control by the hypothalamus (2). Similar to prolactin release (3), MSH secretion is under an inhibitory control by the hypothalamu...

An ln vivo Assay for Biological Activity of Synthesized Recombinant Human Growth Hormone

The role of melanophore hormone of the pituitary in the colour changes of cold and warm blooded animals; a review.

Compared to the anterior and posterior lobe principles, the hormone elaborated by the pars intermedia or middle lobe of the pituitary has received scant attention. This is due to the earlier belief that apart from blackening fish and frogs for some short duration, this hormone which was variously termed chromatophorotrophic hormone, melanophore hormone or intermedin had got no important assignm...

synthesis and characterization of potentially biological active cyclometallated organoplatinum(ii) complexes

this work is presented in five parts. in the first part preparation of the starting complex [pt(c^n)cl(dmso)], 1, in which c^n = n(1),c(2?)-chelated, deprotonated 2-phenylpyridine, and dmso = dimethylsulfoxide, and its reaction with 1 equiv of the biphosphine ligands bis(diphenylphosphino)amine, dppa, or bis(diphenylphosphino)methane, dppm, to give the complex [pt(c^n)cl(dppa)], 2, or [pt(c^n)c...

Expanding beyond biological crystallography.

Institute for Molecular Bioscience, University of Queensland, Queensland Bioscience Precinct, Brisbane, QLD 4072, Australia, Cambridge Institute for Medical Research, Department of Haematology, University of Cambridge, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, United Kingdom, and Photon Science, SLAC and Structural Biology, School of Medicine, Stanford University, 2575 Sand Hi...